Thermo Fisher Scientific Helps Optimize Productivity of Bioequivalence Studies and Regulatory Compliance for CRO Customer

Implementation of Thermo Scientific Watson LIMS at IPRC Enhances the Company’s Information Management, Facilitating Compliance and Improving Efficiencies

PHILADELPHIA (May 24, 2011) – Thermo Fisher Scientific Inc., the world leader in serving science, today announced that International Pharmaceutical Research Center (IPRC) has implemented Thermo Scientific Watson LIMS (laboratory information management system) to improve productivity of its Phase I clinical trials unit while enabling compliance with current regulatory requirements. Since the implementation of Watson LIMS at IPRC’s Phase I unit, the company has benefited from significant productivity improvements, efficient assay validation, timely bioanalysis of samples, seamless instrument interfacing, easy sample tracking and reliable reporting of results.

Watson LIMS is a highly specialized, protocol-driven LIMS for drug metabolism and pharmacokinetic (DMPK) studies and is used as standard in bioanalytical laboratories in 18 of the top 20 global pharmaceutical companies and leading contract research organizations (CROs). It is designed to benefit pharmaceutical companies and CROs by offering secure data transmissions between pharmaceutical sponsor and CROs, helping ensure regulatory compliance, enabling reliable audit trails and thereby improving time to market.

SAGE-N RESEARCH SORCERER PLATFORM IMPLEMENTED BY THE UNIVERSITY AT BUFFALO FOR RELIABLE AND SIMPLE PROTEIN IDENTIFICATION

MILPITAS, 25th May 2011 — Sage-N Research, Inc., the world leader in supplying Integrated Data Appliances (IDAs) for proteomics research, announced that the State University of New York at Buffalo’s pharmaceutical sciences research group has chosen the Sage-N Research SORCERER platform to assist with its advanced proteomics research.

One of the primary reasons for this was to take advantage of the sophisticated algorithms and server capabilities that the SORCERER offers, as an overall life science platform. The SORCERER will replace the current super-computers that are used within the University’s laboratory to characterize and identify proteins and handle the large amounts of data generated from high throughput mass spectrometers.

The Lab of Clinical Proteomics and Pharmaceutical Analysis, led by Dr. Jun Qu, Assistant Professor at The State University of New York at Buffalo and the Chief Scientist in Bioanalysis in CEBLS, has decided to go with Sage-N Research’s SEQUEST 3G search engine and Matrix Science’s Mascot, both hosted on the SORCERER platform, to study a variety of applications including diagnostics and biomarker discovery for cardiovascular diseases, colon, pancreatic and prostate cancer, cocaine addiction, retina degeneration, COPD and HIV.

Optibrium Announces Free Models to Predict Toxicity of Compounds

StarDrop’s Glowing Molecule Provides Visual Link between Chemical Structure and Predicted Toxicities

CAMBRIDGE, UK, May, 25, 2011 – Optibrium, a provider of software solutions for drug discovery, announces the availability of a range of models to help predict the toxicity of potential new compounds. Optibrium has generated a range of Quantitative Structure Activity Relationship (QSAR) models of key toxicity endpoints, based on data made available by the US Environmental Protection Agency (EPA) as part of its Toxicity Evaluation Software Toolkit (T.E.S.T.). The toxicity prediction models were built with the Auto-Modeller module of the newly launched StarDrop 5 and are available to all StarDrop users free-of-charge. To find out more and download the models please visit Optibrium’s on-line community at http://www.optibrium.com/community.

Whether compounds are intended as drugs, cosmetics, agrochemicals or for other industrial applications, it is essential to understand their potential to cause toxic effects. Understanding this can allow scientists to prioritise chemical structures for further research or identify the most appropriate downstream experiments to confirm their safety. However, the ability to predict toxicities in compounds can be extremely challenging.
Models have a high degree of uncertainty in the predictions they make due to the complexity and variety of chemical and biological mechanisms that lead to toxicities.

New Thermo Fisher Scientific Industrial Gas System: Performance, Speed and Sensitivity for Multi-Component Gas Analysis

MADISON, Wis., (May 23 2011) – Thermo Fisher Scientific Inc., the world leader in serving science, today announced enhancements to its Antaris Industrial Gas System (IGS)  that improve performance, speed, ease-of-use and sensitivity. The Antaris IGS now offers faster scan speeds (to 5 Hz at
0.5 cm-1 resolution) and enhanced electronic and communication capabilities to support more rapid scanning. Based on Thermo Fisher Scientific’s renowned Nicolet 6700 Fourier transform interferometer, the Antaris IGS is an FTIR-based analyzer capable of monitoring dozens of gases simultaneously while providing accurate and fast multi-component gas analysis. It is a highly configurable gas analyzer that is used in a wide scope of industrial analyses, particularly in emerging green energy applications such as landfill methane gas analysis. The Antaris IGS is also ideal for the ever-changing needs of the automotive, chemical and environmental industries.

Landfills provide ideal conditions for methanogenesis, with landfill gas comprised of approximately 40-60 percent methane. Today, significant amounts of waste are slowly decaying under the ground in landfill sites, and methane is produced for years after sites are closed. As this methane escapes, either directly into the atmosphere or by diffusion through the cover soil, it greatly contributes to global warming. To mitigate this issue, many landfills deploy gas collection systems that not only prevent escape, but also capture high-quality, contaminant-free gas for use in power generation.
The new Antaris IGS is a key part of this process, providing fast, sensitive and reliable monitoring of landfill methane gas so it can be reused as a source of green energy.

ITT Analytics launches new Bellingham + Stanley digital hand-held refractometer at National Restaurant Association Show

CHICAGO, IL., May 23, 2011 — ITT Corporation (NYSE:ITT) announces the introduction of the Bellingham + Stanley OPTi hand-held refractometer for Brix analysis of beverages and foodstuffs at the National Restaurant Show (NRA) 2011. The OPTi hand-held refractometer is a portable, compact measurement device ideal for the measurement of dissolved solids by cellar services and dispense maintenance engineers in food and beverage retail outlets. The use of the new system will assist the delivery of maximum product yield helping to reduce costs.  ITT Analytics will showcase its products for food and beverage testing in booth 4027 during the NRA Show 2011 from May 21-24 in Chicago, Illinois.

The easy-to-use OPTi digital hand held refractometer provides accurate and rapid measurement of dissolved solids, making it an ideal tool to control the blend ratio and sugar or fructose content of post-mix beverages at point of dispense. With the use of the OPTi refractometer, retail and restaurant outlets are able to ensure product quality and maximum product yield, enabling costs to be easily and effectively controlled. Measurements are completed in two seconds and only a small drop of sample is needed to provide an instant result.

Scott Brothers Ltd. Launches New Soft Storage Product Range at Exclusively Housewares 2011

(18 May, 2011) Scott Brothers Ltd, specialist in storage products for the home, will be exhibiting a new range of soft and flexible storage solutions for the first time, at the 10th Anniversary Exclusively Housewares Show 2011 from 7th – 8th June at the Business Design Centre, London. Scott Brothers will be launching its new home storage solutions including suit and clothes hangers and storage boxes alongside its successful Pack-Mate and Space Bag range of vacuum storage bags, on Stand 237.

Scott Brothers Ltd. is the largest supplier of branded vacuum storage bags in the UK and holds a unique position as the distributor of both the leading brands in this segment - Pack-Mate and Space Bag. The company will be presenting its new soft storage range this year continuing its success in the home storage market and satisfying a need for more flexible storage solutions to make the most of limited space.

Novozymes Biopharma to showcase hyaluronic acid for ophthalmology applications at Joint Congress of SOE and AAO 2011

New recombinant hyaluronic acid for eye care and ophthalmic drug delivery.
Study results to be presented at the 2011 Joint Congress of SOE and AAO.

NOTTINGHAM, UK – May 17, 2011 – Novozymes Biopharma, part of Novozymes A/S, world leader in bioinnovation, today announced that it will be showcasing its hyaluronic acid (HA) product for eye care and ophthalmic drug delivery at the 2011 Joint Congress of the European Society of Ophthalmology (SOE) and American Academy of Ophthalmology (AAO), which will take place from June
4-7 2011 in Geneva, Switzerland. Novozymes will also be presenting its latest scientific poster at the show, highlighting the results of the company’s recent study into the use of HA for ophthalmic formulation. For more information on Novozymes’ HA or to request a copy of the scientific poster, please visit booth #1256 at the Joint Congress of SOE and AAO 2011 or www.biopharma.novozymes.com.

“We are proud to showcase our innovative HA product which, due to its high purity and biocompatibility is ideally suited for use in formulations intended for eye care and ophthalmic drug delivery” comments Hans Ole Klingenberg, Global Marketing Director at Novozymes Biopharma. “We are also delighted to present the results of our latest study into the use of HA in ophthalmology, which provides insight into the increasing need for a high purity HA ingredient for ophthalmic applications.”

Misumaru UK Ltd. Exhibits New Range of Gift Bags at Progressive Greetings Live 2011

Misumaru UK Ltd., specialist distributor of decorative gift bags, is to showcase its unique and diverse Gift-Mate gift bag product range at Progressive Greetings Live 2011, at the Business Design Centre, London from 24th-25th May. This will be the first time that Misumaru UK Ltd has exhibited the gift bag range at Progressive Greetings, following its successful preview in the UK by Scott Brothers Ltd 2010. Misumaru UK Ltd will be presenting the gift bag range on stand 227.

Misumaru is a specialty producer of printed and converted products, with emphasis on product quality, competitive pricing and excellent customer service. Its range of decorative gift bags is now available in the UK via Misumaru UK Ltd., in partnership with Scott Brothers Ltd and also distribution specialists, Riverside Cards. The Gift-Mate bags are available in a variety of sizes to accommodate a range of gifts, including a wine bottle bag. As the gift bags are waterproof and watertight they are also of interest to florists to hold flower bouquets and plants.

Thermo Fisher Scientific Showcases Solutions for Advanced Metals Characterization at CETAS 2011

ECUBLENS, Switzerland (May 10, 2011) – Thermo Fisher Scientific Inc., the world leader in serving science, will highlight its innovative offering of spectroscopy solutions for advanced metals characterization in the steel and metal industries during CETAS 2011, being held May 17–19, in Luxembourg.
Thermo Fisher will showcase a range of solutions to substantially improve automation and workflow within production and process control laboratories.
Among the instruments highlighted will be the Thermo Scientific ARL SMS-2500 automation system, which provides increased power and flexibility for the automatic operation of Thermo Scientific optical emission and X-ray fluorescence spectrometers (OES and XRF). The company will also present an improved method for fast analysis of inclusions in metals using the Thermo Scientific Spark-DAT option. For more information, visit booth #1 during CETAS 2011.

The Thermo Scientific ARL SMS-2500 automation system provides an integrated, workflow-orientated solution that is specifically designed for high-speed production control laboratories in the metals industries. The system ensures increased sample turnaround by tightly integrating sample preparation with a larger, stronger and faster robot. By enabling direct access to the milling machine for the preparation of samples, processing time is reduced and expensive electromechanical sample transfer systems are eliminated. In addition, a choice of different milling machines allows customers to select the best solution depending on their preferences, needs and budgets, including the newly launched Haas Mini Mill with Thermo Scientific ARL PrepControl.

Novozymes Biopharma collaborates with the University of Oslo to develop enhanced albumin fusion technology that tailors the half-life of proteins

Albufuse Flex next-generation technology has been developed to tailor and control the pharmacokinetics of target proteins and peptides for flexible, optimal use.

NOTTINGHAM, UK – May 5, 2011 – Novozymes Biopharma, part of Novozymes A/S, the world leader in bioinnovation, today unveiled its enhanced next-generation albumin technology, which was developed in collaboration with the University of Oslo, Norway, one of the world’s leading institutions in the research of albumin variants and the neonatal Fc receptor (FcRn).
Built on Novozymes’ original Albufuse platform, the proprietary Albufuse Flex technology has been designed to enable users to adapt and control the pharmacokinetics of their target protein or peptide with retained efficacy, ensuring flexibility and optimal use.

“Novozymes Biopharma is thrilled to introduce Albufuse Flex to the  industry,” says Dave Mead, Business Development Director at Novozymes Biopharma. “Albumin is a natural and benign carrier molecule, and by having the unique ability to decrease or increase its half-life it will help our customers to develop novel drugs with improved pharmacokinetic properties for a wide range of applications.”

ERT Announces Appointment of New President and CEO

PHILADELPHIA, PA – 04 May, 2011 ERT, a global technology-driven provider of clinical services and customizable medial devices to biopharmaceutical and healthcare organizations, announced today that its Board of Directors has appointed Jeffrey S. Litwin, M.D. its new President and Chief Executive Officer and as a member of the board.

Dr. Joel Morganroth, who had served as interim President and Chief Executive Officer, commented that "after a thorough national search by Heidrick and Struggles, our Board selected Dr. Litwin, an internal candidate, as the most qualified person to lead ERT.  Jeff brings to ERT knowledge of the Clinical Research domain, that is our core business, and also experience in the adjacent markets of Phase IV safety surveillance and healthcare in which ERT's assets will be employed.  All of our employees look forward to continuing to work with Jeff to enhance ERT's operational successes and strategy."

Dr. Litwin joined ERT in 2000 as Senior Vice President and Chief Medical Officer and was subsequently promoted in December 2005 to Executive Vice President and Chief Medical Officer.  Dr. Litwin oversaw ERT's global cardiac safety operations for seven years and was instrumental in implementing EXPERT, ERT's digital operating system.  During this time period, ERT experienced tremendous growth with revenues increasing more than three-fold. For the last four years, he has been responsible for leading ERT's consulting business, assisting over 150 companies with the design and evaluation of cardiac safety testing programs.  Throughout his career at ERT, Dr. Litwin has also been directly involved in supporting ERT's sales efforts.

Thermo Fisher Scientific Announces Upgrade Program for NanoDrop Instruments that Includes Donations to Academic Institutions in Developing Nations

WILMINGTON, Del. (May 3, 2011) – Thermo Fisher Scientific Inc., the world leader in serving science, today announced a new upgrade program that includes the donation of reconditioned Thermo Scientific NanoDrop 1000 spectrophotometers to academic institutions in developing countries. Owners of a NanoDrop 1000 UV-Vis spectrophotometer can trade in their current instrument and receive a $1,500 credit with the purchase of a NanoDrop 2000 or NanoDrop 2000c UV-Vis spectrophotometer, plus a free one-year extended service plan. Thermo Fisher will refurbish all traded-in instruments and donate them to Seeding Labs, an organization that places scientific instrumentation in the academic institutions of developing nations.

For scientists in poorer countries, the expense of starting up a modern laboratory makes carrying out world-class research nearly impossible. For these researchers, access to equipment, even older models, can mean the difference between building a functional lab and suspending research.
Providing refurbished NanoDrop 1000 instruments through Seeding Labs supports scientific research in these countries and NanoDrop instruments are ideal candidates for this program because they are easy to use and require no consumables.

Thermo Fisher Scientific Launches New Atomic Absorption Spectrometer for Reliable and Dedicated Deuterium Graphite Furnace Analyses

CAMBRIDGE, UK (May 3, 2011) – Thermo Fisher Scientific Inc., the world leader in serving science, today announced the launch of a new compact atomic absorption (AA) spectrometer for dedicated and cost-effective graphite furnace analysis. The Thermo Scientific iCE 3300GF, the latest addition to the iCE 3000 Series range of AA spectrometers, is well-suited for economically conscious laboratories. It offers guaranteed deuterium background correction and automatic optical set-up, ensuring optimal sensitivity, reliability and accuracy of results.

Developed for a range of analytical applications across environmental, academic, clinical and food safety laboratories, the iCE 3300GF AA spectrometer includes features that provide high levels of sensitivity and efficiency for trace elemental analysis. The iCE 3300GF AA spectrometer offers an integrated furnace autosampler for preparing standards and intelligently diluting over-range samples, as well as an Ebert optical system. This significantly increases productivity by enabling automatic and unattended operation. In addition, the new instrument offers a unique graphite furnace vision system (GFTV), which provides a real-time internal view of the graphite cuvette, allowing observation of sample deposition and drying behavior and enhancing overall method development.